Optimind vs Alpha Brain

Cindy Wilson Thumbby Cindy Wilson
BS, Dietetics and Nutrition

In the world of nootropic supplements, Alpha Brain and Optimind have a leading position. They are dietary supplements that stimulate brain activity, cognitive function and enhance concentration. Both products claim outstanding mental performance, superior brain activity, and memory gain.

However, many customers are utterly perplexed about which one is the one that fits their needs best. When inquiring about them online, you’ll come across positive reviews for the two, which adds to the confusion. 

Therefore, we made a side-by-side comparison and inquired in-depth information about Alpha Brain and Optimind. So, in this article, you will find out how they are made, the benefits they deliver, and if and what their side effects might be. 

Check what’s the best-rated brain nootropic stack

Optimind and Alpha Brain – Nootropic Supplements

Nootropics are dietary supplements that boost brain function, increase cognitive capacity and help fight stress and anxiety. These substances are not drugs and are generally taken by healthy individuals who need to stimulate their thinking and learning capacity. 

The popularity of mind-stimulating supplements has roof-topped over recent years. The market today abounds in offering a wide range of brain stimulants. Yet, not all of them are deemed equal, and there is a fierce struggle among manufacturers to offer nootropics that stand to the claims they make. 

Alpha Brain and Optimind are among the most sophisticated market offers available today. From their cutting-edge production facilities to the purest ingredients used in their formulas, both products are sophisticated and clinically tested. Both manufacturers boast proprietary formulas and clinical studies to support their efficacy claims. In line with this, numerous online reviews seem to prove that both Alpha Brain and Optimind deliver beneficial effects to their users. Besides, both products claim that they are energy boosters as well. 

Even though the FDA doesn’t review nootropic supplements, the whole manufacturing process is strictly controlled and monitored. Both products have undergone rigorous trials and testing. Yet, bear in mind that Alpha Brain and Optimind are over-the-counter supplements, and you don’t need any prescription for them. This means they are not intended to diagnose, prevent, treat, or cure any disease. 

Optimind – General Information


What is OptiMind Advantage?

  • Usage of clinically proven nootropic ingredients for focus and energy
  • 100% Money-back guarantee
  • Made in the USA

Advertised to boost energy, focus, and cognition, Optimind quickly got the general public’s attention as it has been promoted on various websites. But surely it is not because of the marketing hype, as the product has been used by millions of people, swearing to its cognition-boosting effects, including focus and concentration. 

According to the company, you’ll need to be using Optimind for about 12 weeks to achieve optimal results. However, if you don’t feel like using it or don’t think it has added significant benefits to your brain health, or if you happen to experience any possible adverse effects, you can use your 30-day money-back guarantee. 

Optimind – Ingredients and Features

What makes Optimind such a powerful nootropic is the use of a powerful blend of ingredients. The blend of various ingredients makes Optimind a nootropic stack carefully dosed with ingredients known to have a special effect on brain functions. 

The nootropic stack in Optimind is comprised of Synapsa extract- Whole Plant Extract (derived from the Bacopa Monnieri plant), L-Taurine, Natural Caffeine, Phosphatidylserine 50% powder, Tyrosine, and Huperzine A. In addition, the formula also contains Vitamin D, Calcium, Turene, Vitamin B12, Sulbutiamine, GABA, and Alpha Lipoic Acid. 

What is the role of these ingredients, and how do they stimulate cognitive and mental processes? 

The key ingredient, Synapsa, is extracted from the Bacopa Monnieri plant naturally found in India. It has long been known to improve brain function, focus, and retention, and numerous clinical trials have proven its effectiveness.  The patented concentration of Bacopa in Optimind is 55%, claiming to be the strongest globally.

Huperzine A is a Chinese herb that has long been used in Chinese traditional medicine. It enhances circulation, relieves pain, and reduces stress and anxiety. Clinical studies have shown that Huperzine A has neuroprotective effects.

Caffein is a well-known cognitive and energy booster, naturally occurring in many herbs and plants, such as green tea and coffee. If you are an eager coffee drinker, then you could think of lowering the amounts of coffee you drink daily. The amount of caffeine in Optimind is 75mg, enough for a quick start to your working day, so you could test if this caffeine amount is sufficient for your needs.

Phosphatidylserine is a substance naturally occurring in soybeans. It maintains brain cells and their activity. With 50% extracted in its purest form, it will stimulate your brain cells to store and send information swiftly. Tyrosine is a substance that the military has long been using. Tyrosine stimulates brain performance and enhances focus and concentration even under stressful and demanding conditions. 

The compound of this nootropic stack is additionally supported by vitamins and amino acids that allow your brain to think clearly. The stimulative role they have is likely to clear out brain fog and maintain overall brain health. 

Optimind – Safety and Usage

Optimind ingredients have been produced in facilities that follow GMP (Good Manufacturing Practices) in a strictly controlled and monitored environment. All the ingredients are grown with the help of solar-powered equipment to ensure the finest quality. 

The recommended starting dose for healthy adults is 1-2 capsules every morning with a glass of water and light meal. Depending on your needs, you can increase it to up to 4 servings per day. The maximum allowed dose is eight within 24 hours. The short-term benefits become evident after a few weeks, while you need to take them consistently for a longer period of time for long-term effects.

Optimind is not recommended for pregnant and nursing women. If you have an existing medical condition, you need to consult your doctor before you start taking them. Optimind is not intended for persons under the age of 18. 

Clinical Trials Behind Optimind

Optimind ingredients have been a subject of numerous tests and trials. The same refers to the ingredients used in the product. 

Bacopa is clinically proven to enhance thinking skills and memory, while caffeine and amino acids are also used in medicine to treat attention disorders and stimulate neurotransmitters.

Caffeine increases mental alertness, cognitive processes, and overall body performance. The amount used in Optimind is relatively high. However, as tested on a significant number of adults, it won’t make you crash during the day or give you jitters. Here, L Taurine plays a significant role as it lowers blood pressure and relaxes the nervous system.

In essence, all of the ingredients used in Optimind have been tested and proven effective in enhancing memory, thinking, and learning. 

Alpha Brain- General Information 

Alpha Brain

How Does Alpha Brain Help?

  • Usage of earth-grown ingredients like Bacopa, Cat’s Claw, Oat Straw and Huperzia Serrata
  • Memory, focus and concentration without the crash
  • Perfect for careers, academics, social life or atheltics

When comparing Optimind Vs. Alpha Brain, we noticed some similarities, but also some considerable differences. Alpha Brain is advertised as a nootropic stack that supports memory and focus, clears the brain fog, and aids cognitive processing. 

The most prominent feature of Alpha Brain is its ability to keep you ‘in the zone’ state of mind, i.e. when your concentration and focus are the most intense. Also, many satisfied users claim that regular use of Alpha Brain increases your energy levels, helps you perform complex tasks, and react quickly, even in highly stressful situations. 

Alpha Brain – Ingredients and Features 

Alpha Brain consists of three nootropic stacks comprised of a blend of ingredients proven to stimulate mental and learning processes. These proprietary stacks (called Onnit) affect three mental areas for maximum brain stimulation. 

Onnit Flow Blend is comprised of L-Tyrosine, oat straw extract, L-Theanine, Phosphatidylserine, and Cat’s Claw extract (Uncaria tomentoa). These ingredients stimulate those brain areas that allow you to reach optimal focus, i.e., the flow state when distractions seem not to affect you. 

Onnit Focus Blend includes L-Alpha glycerylphosphorylcholine (Alpha GPC), Bacopa (Bacopa Monnieri) Extract, Toothed Clubmoss (Huperzia Serrata) whole extract. It aims to activate your ability to focus more, remember details, and work on complex activities.

Onnit Fuel Blend is another stack comprised of L-leucine and Pterostilbene, a powerful blend of amino acids responsible for protein synthesis and energy boost. 

In addition to these three distinctive stacks, the formula includes vitamin B6, which affects neurotransmitters and the overall immune system. Unlike Optimind, Alpha Brain’s formula doesn’t include caffeine for extra alertness and energy. 

How Does Alpha Brain Work?

Alpha Brain directly stimulates mental performance by increasing the production of neurotransmitters and activating the brain to make more Alpha waves. Neurotransmitters send information from and to the brain, while Alpha waves play a role in memory storage and cognitive processes. 

Alpha Brain activates all mental processes with the help of its formula’s stacks. For instance, the Onni Flow Blend is an amino acid that increases the dopamine and serotonin release in the brain. These two hormones induce the feeling of being relaxed, which is known to induce Alpha waves activity. 

The Onni Focus Blend contains a compound that aids the production of acetylcholine. Acetylcholine is one of the most important neurotransmitters in the human body that controls nerves, hormonal glands, and muscle cells. Together with Vitamin B6, which is also contained in the Alpha Brain formula, create optimal levels of neurotransmitter production. 

Alpha Brain – Safety and Usage

Alpha Brain is intended for healthy adults who need mental and energy enhancement. Pregnant or nursing women and individuals with existing or suspecting medical condition must consult their doctors for further instructions. Before taking Alpha Brain capsules, make sure you are not allergic to any of the ingredients above. 

The recommended dose for Alpha Brain is two capsules per day taken with a light meal. You should avoid taking more than the recommended dose as it might have an adverse effect.

Clinical Trials Behind Alpha Brain

Onnit claims that behind Optimind, there’s been rigorous research and multiple clinical studies. The research is based not only on how the ingredients affect the human brain but also on growing and sourcing them. All their products are tested by a third party for purity so that any competing athlete can use them at any time. Alpha Brain is certified by UTZ and Rainforest Alliance.

Also, similar to Optimind, most of the ingredients have been clinically tested, and some are used for medical purposes. This refers to both chemical compounds and natural herbs. In addition, the amount of each ingredient has been clinically tested and adjusted to meet people’s optimal needs.

The Difference Between Alpha Brain and Optimind

Alpha Brain Vs Optimind

Alpha Brain and Optimind are considered the best nootropics currently on the market. They are promoted on various sites and endorsed by people of various professions (take Joe Rogan, for instance), but they seem to match the description. They have thousands of positive online reviews, and many pharmacists and physicians recommend them. 

From the ingredients list, it is evident that Alpha Brain and Optimind share some of the ingredients. Both nootropics include Bacopa Monnieri, Huperzia Serrata Extract, phosphatidylserine, and Vincpocetine in their formulas. But this where commonalities end.

Alpha Brain contains a wider range of nootropic ingredients and a different set of vitamins and amino acids, such as Vitamin B6, L-Theanine, oat straw extract, AC-11, Alpha Lipoic Acid, and L-Leucine.

Alpha Brain doesn’t have caffeine in its formula, so it might appeal more to caffeine sensitive or those who can’t give up their coffee. Yet, Optimind has taurine, a substance known to calm the nervous system down, reducing the crash or the jittery effect the caffeine might deliver.


What Benefit Does Bacopa Monnieri Deliver?

Bacopa is clinically proven to enhance thinking skills and memory, and it is used in medicine that treats Alzheimer’s disease, ADHD, anxiety, and other conditions. Bacopa Monnieri is thought to increase the number of chemicals that stimulate memory skills and learning capacities. Some studies have also shown that it protects the brain cells from chemicals related to Alzheimer’s disease, even though those studies are not conclusive. 

Alpha Brain vs Optimind – Which Works Better?

When choosing the best nootropic, it is important to consider a few things- the ingredients, the effect they deliver, and possible side effects. Having said this, the best is the one that delivers maximum results for you. 

Alpha Brain and Optimind, as explained above, share some ingredients, among which Bacopa claimed to deliver optimal cognitive enhancement. Yet, there are differences between the two.

Alpha Brain’s numerous compounds include  AC-11 or so-called Cat’s Claw, an ingredient that supposedly has the power to unleash your mind’s potential. Onnit claims that Alpha Brain will not only affect your mind, but it will increase your energy, alertness, improve your sleep quality, and positively affect your body health.

Users also claim that Optimind delivers short and long-term effects focused on improving cognitive functions, attention, retention, and energy. It contains caffeine that boosts energy and taurine that works against feeling jittery.

Are Alpha Brain and Optimind Worth the Money?

Numerous users claim that Alpha Brain and Optimind have given them unequaled brainpower, energy and cleared the brain fog. These benefits come with a price, but once you feel the difference, you’ll realize they are worth the money.

Both products offer a money-back guarantee if you aren’t satisfied, and Optimind offers 10 free capsules and free shipping. Alpha Brain’s price is slightly higher, but the serving per day is limited, while Optimind’s dose can be increased to up to 8 servings per day.


  1. Abdul Manap, Aimi Syamima, Vijayabalan, Shantini, et all. Drug Target Insights, 2019. Bacopa monnieri, a Neuroprotective Lead in Alzheimer Disease: A Review on Its Properties, Mechanisms of Action, and Preclinical and Clinical Studies.DOI: 10.1177/1177392819866412.
  2. Singh, Babita, Pandey, Shivani, Rumman, Mohammad, Mahdi, Abbas Ali. Metabolic Brain Disease, 2020. Neuroprotective effects of Bacopa monnieri in Parkinson’s disease model. DOI: 10.1007/s11011-019-00526-w. 
  3. Kennedy, David O., Wightman, Emma L. Advances in Nutrition, 2011. Herbal extracts and phytochemicals: Plant secondary metabolites and the enhancement of human brain function. DOI:10.3945/an.110.000117
  4. Vitthalrao, Leena Sakhare. Journal of Drug Delivery and Therapeutics, 2018. Nootropics Agents: Pharmaceutical Aspect, Common Examples, And Their Applications. DOI: 10.22270/jddt.v8i5-s.1940.
  5. Forest, W, Pfeifer, A, Muhs, A.Journal of Alzheimer’s Disease, 2013. Cognitive enhancers (Nootropics). Part 3: Drugs interacting with targets other than receptors or enzymes. Disease-modifying drugs. ISSN: 1387-2877
  6. Spence, Justin, Chintapenta, Monica, Kwon, Hyanggi Irene, Blaszczyk, Amie Taggart. Consultant Pharmacist, 2017. A brief review of three common supplements used in Alzheimer’s disease. DOI: 10.4140/TCP.n.2017.412. 
  7. Solomon, Todd M., Leech, Jarrett, Debros, Guy B., Murphy, Cynthia A, Budson, Andrew E., Vassey, Elizabeth A. Human Psychopharmacology, 2016.  A randomized, double-blind, placebo-controlled, parallel-group, efficacy study of alpha BRAIN® administered orally.  DOI: 10.1002/hup.2520.
  8. Stinson, Bruce, Arthur, David. Complementary Therapies in Clinical Practice, 2013. A novel EEG for alpha brain state training, neuro biofeedback, and behavior change. 10.1016/j.ctcp.2013.03.003.
  9. Vergouwen, T., Povel, E., Bakker, B., Koerselman, F., Verheij, T. European Neuropsychopharmacology, 2002. Randomized controlled trial of a depression management program (OPTIMIND) in primary care: Impact on compliance and dropout. DOI: 10.1016/s0924-977x(02)80222-x.

About Author

Cindy Wilson Thumb
BS, Nutrition & Food Science | Connect with on LinkedIn
Cindy Wilson

Hello, I am Cindy, and this a website where I inspect everything related to nutrition and a healthy lifestyle. I have a BS in Dietetics and Nutrition (Kansas State University) and have completed a dozen specialty courses related to nutrition, biochemistry, and food science. I am open to learning more, but foremost I would like to share all my knowledge with you.

Scroll to Top