Cebria vs Prevagen

Cindy Wilson Thumbby Cindy Wilson
BS, Dietetics and Nutrition

Memory loss can be a real issue that seriously interferes with the ordinary course of life. The aging process irreversibly slows the brain function down, resulting in gradual mental decline and forgetfulness. The symptoms can vary from minimal, such as forgetting where you left your car keys and what you were about to do to extremes, such as forgetting your address or even your name!

While cognitive decline is a natural, age-related process, much research has shown that it can be controlled or even boosted. Of course, we are not discussing prescribed medicine strictly controlled by a doctor but supplements that can positively support cognitive abilities. In case you’ve been struggling with memory loss, you must have been advised at some point to try taking over-the-counter memory boosters.

Suggestions might vary, from vitamins and over-the-counter drugs to prescribed medicine. Yet, dietary supplements that affect cognition and improve memory are among the most popular choices, and Cebria or Prevagen have been among the most recommended and positively reviewed. These two products have been touted to improve memory, boost thinking processes, and enhance overall brain health.

So, in this article, we will review Cebria vs Prevagen and provide you with important information about their effect, the benefits they deliver, and possible side effects.

Check what’s the best rated brain nootropic stack

What Kind of Supplements Are Cebria and Prevagen?

Cebria and Prevagen belong to the group of nootropics, i.e., dietary supplements that are deemed to improve the overall cognitive function, prevent memory loss, and boost creativity. Nootropics are not medicine, and they are generally taken by otherwise healthy individuals who feel that they need memory enhancers.

Nootropic supplements have become increasingly popular over recent years. Many of them are claimed to deliver multiple benefits and protect the mental health of users. However, their use and beneficial effect have still been a subject of ongoing research, and there’s still no definite consensus that confirms their efficiency.

Since they aren’t drugs, you can freely buy them from any store that sells dietary supplements. Cebria and Prevagen are produced in a controlled manufacturing environment. Also, comprehensive research is carried out on any of the ingredients used to produce them. Both products are partially made from natural ingredients clinically proven to support brain function and treat mild memory loss.

However, it is worth noting that the FDA hasn’t evaluated any nootropic supplements. Most of them are not used to treat, prevent or cure any age-related or brain-related disease. This refers to Cebria and Prevagen as well, so they are classified as supplements, and therefore can’t replace any treatment, nor can they substitute a healthy diet regime.

Cebria – General Information

Cebria Reviews

How Does Cebria Help?

  • Premium brain health supplment with natural memory formula
  • Backed by science
  • Safe and effective with GMP
  • Guaranteed satisfaction with 30-day unconditional satisfaction guarantee

The manufacturer advertises Cebria as a memory fortifying supplement that helps aging individuals prevent memory loss and boosts concentration, focus, attention, and processing speed. It is claimed to show significant memory improvement in two months thanks to its proprietary formula. Cebria contains many brain-stimulating substances that have been scientifically proven to improve short-term memory, support mental clarity, and sharpness, and enhance retention and recall.

What Ingredients Does Cebria Contain?

The key ingredient that the manufacturer takes pride in is ashwagandha extract, deriving from Ayurveda herb, found in India. Ashwagandha has been used for decades in Indian traditional medicine, and even centuries ago, it was known to support thinking processes and memory gain. In Cebria, the Aswagandha extract is highly concentrated without being diluted by any chemical solvent or alcohol, and this extract is known as KSM-66.

In addition to Ashwagandha extract, Cebria’s formula contains a blend of brain-stimulating ingredients clinically proven to support brain vitality. These ingredients include B vitamins (Folic Acid, B6, and B12) and green tea leaf extract, proven to stimulate blood flow, energy, and memory function.

Besides the natural ingredients, the formula contains serine, aspartic acid, lactose, valine, tyrosine, histidine, isoleucine, threonine, arginine, leucine, lysine, glutamic acid, methionine, and tryptophan. Some of these amino acids, such as serine, are used for treating cognitive disorders and insomnia. Tyrosine, for instance, is beneficial for fast thinking and memory gain, while arginine is a powerful neurotransmitter that relaxes blood vessels and improves circulation. This means that Cebria is not an all-natural product, despite the key ingredients being natural.

Safety and Side Effects

Cebria is a supplement produced in a controlled environment, following Good Manufacturing Practices (GMP) established by the FDA to ensure that the quality is sustained. Thera Botanics, the company that produces Cebria, claims that the amount of each ingredient is in line with the recommended daily intake. And even though it is not an all-natural product, the chemical ingredients used in the formula are of minimal quantity.

So far, no side effects have been reported, making Cebria a safe brain-enhancing supplement. Yet, as with all other supplements, you need to make sure that you are not allergic to any of the ingredients used in the formula before you start using Cebria. Make sure that you don’t exceed the daily recommended dose of one capsule a day.

The Science Behind Cebria

All primary ingredients have been used in medicine for a long time and have been clinically proven to help boost brain functions and short-term memory. The Ashwagandha extract has not only been used for centuries in traditional Indian medicine, but it has been a subject of clinical testing for 14 years.

Ixoreal Biomed, the company that has performed the study, was able to derive a concentrated extract from the roots of the Ashwagandha plant without using any solvents or alcohol. This pure extract was named KSM-66, and it is part of Cebria’s formula.

The rest of the ingredients have also been widely used in many drugs, so all of them have been part of research that confirms their safety and efficiency.

Prevagen- General Information


How Does Prevagen Help?

  • Apoaequorin, the unique, high quality ingredient in Prevagen
  • Does not require a prescription
  • Easy to swallow

Better Nutrition, the manufacturer behind Prevagen, advertises the product as a memory stimulating supplement that can improve all aspects of cognitive function. Prevagen is claimed to promote a healthy brain and helps in reducing brain fog leading to sharper and faster thinking. According to Nielsen data, Prevagen is the number one America’s selling brain-stimulating supplement. In 2020, it received the “Best of Supplements Winner Award,” while it was voted ‘ The most recommended memory support brand‘ by pharmacists in a 2018-2019 survey conducted by Pharmacy Times.

What Ingredients Does Prevagen Contain?

Like Cebria, Prevagen also takes pride in offering a proprietary formula that helps tackle age-induced mild memory loss. The key ingredient used in the formula is apoaequorin, an ingredient found in glowing jellyfish in the 1960ies. The luminescent compounds of the jellyfish intrigued researchers, and multiple studies have been done to confirm the beneficial properties of apoaequorin to the human brain and its functions. The research results showed that it is a protein that binds with calcium and regulates thinking skills.

In addition to apoaequorin, Prevagen’s formula contains vitamin D, microcrystalline cellulose, maltodextrin, and vegetable capsule. With less than 2%, it also contains casein, peptones, magnesium stearate, lactose, soy peptones, salt, modified corn starch, and sugar.

Safety and Side Effect

Prevagen is considered a very safe product with minimal or almost no side effects. These claims have been made based on the three peer-reviewed studies that have proven the safety of apoaequorin and Prevagen. They published their results claiming that no adverse effects have been observed when taking Prevagen for a longer time.

One study has even shown that even if you exceed the daily dose 16 000 times, it won’t have any negative effects, fortifying the safety claims made by the manufacturer. The company claims that over one million people have tried Prevagen with no side effects or contraindications. The recommended daily dose, though, is one capsule a day, with or without food.

The Science Behind Prevagen

Despite not being approved or evaluated by FDA, Prevagen has been part of a study to prove its efficacy in tackling age-related mild memory loss and cognitive performance.

A study on apoaequorin had led to the creation of a biotech company called Quincy Bioscience. It continued researching the potentials of apoaequorin to help older people improve their cognitive processes and quality of life. Therefore, Prevagen is initially based on long-term studies.

To further enhance the beneficial effect that Prevagen help on aging individuals, a double-blinded study was carried out in a clinical trial with healthy participants over 40 years old.  There was also a controlled subgroup of participants that had mild age-related brain dysfunction. They were given one Prevagen per day in three months.

The clinical trial included a quantitative computerized cognitive assessment tool that performed various quantitative measures. Within those three months, they measured quantitive brain performance in five different intervals.

The results have shown that Prevagen is indeed effective, measuring higher on several scales against the placebo. The measures where Prevagen was effective include those related to the executive memory and thinking processes.

Cebria Vs. Prevagen – Similarities and Differences

When comparing Cebria Vs. Prevagen, it is clear that these two supplements have an identical purpose, i.e., to promote healthy brain performance but differ in their ingredient content. Both products boast high efficacy in improving brain health, memory, and overall wellness.

One striking difference, though, is their composition and vitamin complex included in their formula. Cebria is an herbal-based supplement and has a B vitamin complex, while Prevagen boasts a breakthrough formula with the key ingredient derived from a jellyfish. Since it is a rather new ingredient, it is natural to expect more studies that confirm its efficacy and make sure it is safe to use.

Regarding Cebria, the number of studies confirming its effect is relatively low. However, most of the ingredients in the formula have been widely used over the years, implying its safety and efficiency.


Can Cebria and Prevagen Slow Down Age-Related Memory Loss?

While there is no official FDA confirmation that nootropic supplements work on preventing or treating mental functions and brain health, numerous studies confirm the effect of the ingredients used in their formulas.

Regarding Cebria, the ashwagandha extract has long been known to improve memory and concentration and combined with the vitamin complex; it can have a beneficial effect on the brain and the body.

Prevagen has been tested multiple times, and its effect has been measured to a certain degree. Thousands of users have reviewed it as helpful and very efficient. Yet, it is not FDA reviewed or approved, and it is not considered a drug that prevents or treats underlying aging issues.

Do Prevagen and Cebria Improve Brain Function or Maintain Brain Health?

While there is no conclusive confirmation, they directly affect the normal functioning of the brain. According to numerous reviews, they do have a substantial effect when used regularly.

So far, it is officially known that no nootropic supplement has the power to prevent a brain-related disease. They are intended to maximize the cognitive potential and help maintain brain vitality. However, scientists found that they can have many benefits for aging patients who suffer certain brain disfunction.  The benefits of the substances are tested and confirmed so that they can improve the overall mental condition.


  1. Lopresti, Adrian L., Smith, Stephen J., Malvi, Hakeemudin., Kodgule, Rahul. Medicine (United States), 2019.   An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract: A randomized, double-blind, placebo-controlled study. DOI10.1097/MD.0000000000017186.
  2. Salve, Jaysing., Pate, Sucheta., Debnath, Khokan., Langade, Deepak. Cureus, 2019. Adaptogenic and Immunomodulatory Activity of Ashwagandha Root Extract: An Experimental Study in an Equine Model. DOI. 10.7759/cureus.6466.
  3. Priyanka, G.Anil Kumar.B., Lakshman, M., Manvitha, V., Kala Kumar, B. Frontiers in Veterinary Science, 2020. Adaptogenic and Immunomodulatory Activity of Ashwagandha Root Extract: An Experimental Study in an Equine Model. DOI: 10.3389/fvets.2020.541112.
  4. Spence, Justin, Chintapenta, Monica, Kwon, Hyanggi Irene, Blaszczyk, Amie Taggart. Consultant Pharmacist, 2017. A brief review of three common supplements used in Alzheimer’s disease. DOI: 10.4140/TCP.n.2017.412.
  5. Bioscience, Quincy. Pharmacy Times, 2020. Pharmacists’ Guide to Recommending Prevagen®. ISSN 00030627.
  6. Onaolapo, Adejoke Yetunde, Obelawo, Adebimpe Yemisi, Onaolapo, Olakunle James. Current Aging Science, 2019. Brain Ageing, Cognition, and Diet: A Review of the Emerging Roles of Food-Based Nootropics in Mitigating Age-related Memory Decline. DOI: 10.2174/1874609812666190311160754.
  7. Vitthalrao, Leena Sakhare. Journal of Drug Delivery and Therapeutics, 2018. Nootropics Agents: Pharmaceutical Aspect, Common Examples, And Their Applications. DOI: 10.22270/jddt.v8i5-s.1940.
  8. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 2013. ALSUntangled No. 18: Apoaequorin (Prevagen). DOI: 10.3109/17482968.2012.727302.
  9. Morè, Lorenzo, Lauterborn, Julie C., Papaleo, Francesco, Brambilla, Riccardo. Neuroscience and Biobehavioral Reviews, 2020. Enhancing cognition through pharmacological and environmental interventions: Examples from preclinical models of neurodevelopmental disorders. DOI:10.1016/j.neubiorev.2019.02.003

About Author

Cindy Wilson Thumb
BS, Nutrition & Food Science | Connect with on LinkedIn
Cindy Wilson

Hello, I am Cindy, and this a website where I inspect everything related to nutrition and a healthy lifestyle. I have a BS in Dietetics and Nutrition (Kansas State University) and have completed a dozen specialty courses related to nutrition, biochemistry, and food science. I am open to learning more, but foremost I would like to share all my knowledge with you.

Leave a Reply

Your email address will not be published. Required fields are marked *

Scroll to Top